Blackhead closure usually refers to open acne. Acne is caused by poor excretion of sebum from the follicle and keratinized cells shed from the follicle wall, which are adhered and blocked in the follicle. Melanin deposition and lipid oxidation may be the cause of its black color. Patients can be relieved by topical medications, chemotherapy, acne removal surgery and physical therapy. 1. Topical medication: patients can use topical retinoic acid cream, which can improve the keratinization of sebaceous gland ducts of hair follicles and dissolve local acne symptoms, which is conducive to the improvement of patients’ symptoms. 2. Chemical treatment: fruit acid skin resurfacing can also be used to treat closed mouth acne, because fruit acid can interfere with cell adhesion on the cell surface, accelerate the epidermal cell shedding and renewal, regulate sebaceous gland secretion to alleviate the phenomenon of local blackheads. 3. Acne removal: For the phenomenon of facial blackheads, patients can use acne needles to squeeze out the contents, but be careful to require professional medical personnel to operate. 4. Physical therapy: patients can be photodynamic, red and blue light, laser and other physical therapy, mainly as an auxiliary treatment of blackheads and acne and after treatment. It is recommended that patients should go to the hospital after the blackhead phenomenon, follow the doctor’s instructions to deal with it, and not blindly use medicine.