Given that many drugs can freely pass through the placenta, the following points should be considered before administering them: 1. No drug is absolutely safe for the development of the fetus. 2. Medication should be considered during pregnancy only if the benefits of the drug to the mother outweigh the risks to the fetus. If possible, avoid any medication in the early stages of pregnancy (first trimester). 3. The effect of the drug on the fetus may be different from the pharmacological effect expected to occur in the mother. 4.Some drugs may have late onset adverse effects on the fetus. 5.The metabolism of drugs is significantly slower during pregnancy than during non-pregnancy. 6.The use of drugs that have been shown to be teratogenic in pregnant women is prohibited. 7. The experimental use of drugs during pregnancy is prohibited. The U.S. Drug and Food Administration (FDA) classifies the side effects of drugs in pregnant women into the following classes: Class A (pregnancy A): after controlled studies in the first trimester failed to find problems. B grade (pregnancy B): no problems were found in animal tests, but data from human studies are still lacking; or although there were positive findings in animal tests, no adverse effects on the fetus were found in human studies. C grade (pregnancy C): teratogenic effects in animals, but sufficient human studies are lacking, or sufficient research data are lacking in humans. D grade (pregnancy D): Definitely adverse to the fetus, but must be used in certain critical situations in pregnant women. X-grade (pregnancy X): proven in both animal and human studies to be detrimental to the mother and fetus or to do more harm than good. The above classification refers only to the side effects of a drug for most pregnant women and does not exclude individual differences. Also, since some drugs may have late onset of adverse effects on the fetus (i.e., appearing in early childhood or children), the information on drugs with a longer history of use is more mature and reliable than that on newer drugs. The use of commonly used psychotropic drugs for pregnant women is listed below according to the above-mentioned grades: I. Anti-psychotic drugs 1, phenothiazines: pregnancy C grade. Including chlorpromazine, trifluoperazine, methiodiazine, etc. There is insufficient information on other drugs. 2. Thiazides: Insufficient information on the classification. Including Teldene, chlorothiazide, etc. 3.Butylphenols: Haloperidol is a pregnancy C grade. 4.Risperidone (Vistone): Pregnancy C file. 5.Olanzapine (Repro), Quetiapine (Seroquel, Qivi) are pregnancy C grade, must be used when the benefits outweigh the disadvantages. 6.Sulpiride: It has been used for antiemetic in pregnant women and has not been reported to be teratogenic, but there is insufficient information on the classification. 7.Clozapine: Pregnancy B grade. There are more studies on the effects of this drug on pregnant women. The drug description of clozapine does not recommend the use of this drug in pregnant women. Antidepressants 1, tricyclic: amytriptyline, pregnancy D; chlorpromazine, doxorubicin are pregnancy C. 2, tetracyclic: Maprotiline is pregnancy B. 3, SSRIs: citalopram (Xipomol), fluvoxamine (Lanzhi) is pregnancy C. Fluoxetine (Bupropion, Uco, etc.), paroxetine (Sellett), sertraline are pregnancy B. 4, mirtazapine (Remeron): pregnancy C, but human studies There are still few human studies. 5. Trazodone (Meperidine): pregnancy C. 6. Mianserin: pregnancy C. 7. MAOI drugs: pregnancy C. 3. Anxiolytics and sedative-hypnotics 1. Benzodiazepines (Valium): alprazolam, chlordiazepoxide, diazepam (Valium) and lorazepam (Rolla) are pregnancy D. Clonazepam is pregnancy C. 2. Buspirone: pregnancy B. 3. Synthroid (Zolpidem): pregnancy B. 4. Beta receptors Blockers: Tipsan for pregnancy C. IV. anticonvulsants 1. carbamazepine: pregnancy C. 2. sodium valproate (valproate): pregnancy D. 3. phenytoin: pregnancy D. 4. phenobarbital: pregnancy D. 5. lamotrigine: pregnancy C. 6. gabapentin: pregnancy C. 5. lithium salt (lithium carbonate): pregnancy D. 6. puzzle drugs 1. donepezil: pregnancy C. 2. esnon: pregnancy C. 3. galantamine: animal Use has been shown to cause mild fetal and neonatal dysplasia. Finally, it should be reminded that those psychotropic drugs not listed above are not meant to be safe.