The patient was a male, 45 years old. He was admitted to the general surgery department of a secondary hospital in Yangzhou area with persistent and progressive abdominal pain for 3 hours. On admission, ultrasound, routine blood tests and clinical examination suggested ruptured hepatic nodule bleeding. The patient was a carrier of hepatitis B virus in the past. An emergency dissection was performed under general anesthesia. Intraoperatively, massive intra-abdominal bleeding was seen, and about 4000 ml of bloody fluid was aspirated. The liver was covered with nodules of various sizes, and an exophytic nodule of 6 cm in diameter was ruptured and bleeding between the right hepatic segment and segment. The attending surgeon performed suture repair of the ruptured hepatic nodule and filled the surface of the rupture with oil gauze to compress the bleeding, and did not perform selective ligation of the hepatic artery in consideration of the patient’s obvious cirrhosis. More than 10 hours after the operation, the patient’s vital signs were unstable and the abdominal drainage tube continued to draw out 1600 ml of bloody fluid. I went to the emergency consultation, and after reviewing the condition, I recommended emergency hepatic artery selective embolization under DSA, enhanced liver protection, nutritional support, and prevention of abdominal infection. The patient’s abdominal drainage fluid was light bloody fluid, mainly ascites, but the patient presented clinical syndromes of severe hypoproteinemia, sharply elevated transaminases, respiratory alkalosis, gastrointestinal dysfunction, coagulation dysfunction and other multi-organ insufficiency, and was urgently transferred to our department in our hospital for treatment. Four days after the transfer, after active treatment, the vital signs are stable and the functions of all organs tend to improve. The patient’s condition is now basically stable, but he is still not out of danger. The proportion of hepatitis B virus carriers in the population is extremely high, around 10%. Most of them are asymptomatic carriers. After a long period of latency and integration of the virus with liver cells, it can lead to cirrhosis, post-hepatitis B, liver cancer and other diseases that seriously endanger life and health and affect the quality of life. Therefore, when hepatitis B virus carriers are found by physical examination, they should regularly follow up at a specialist clinic! Hepatitis B virus infection is a systemic, chronic disease, and once it is detected, we should insist on working and living normally while paying attention to its development and lifelong follow-up and treatment!