High blood pressure after taking medication caused by neck and shoulder pain, need to consult a doctor in a timely manner, under the guidance of the doctor to change other antihypertensive drugs or change the dosage. Normal adults in a quiet state, blood pressure range systolic blood pressure <140mmHg and diastolic blood pressure <90mmHg, and three times not measured on the same day blood pressure systolic blood pressure ≥140mmHg and/or diastolic blood pressure ≥90mmHg can be diagnosed as high blood pressure. When blood pressure cannot be controlled within the desired range after treatment with lifestyle interventions, it can be treated with hypertension medications. Common hypertension medications include hydrochlorothiazide, metoprolol, nifedipine, and valsartan. After taking them, they can reduce extracellular volume, lower peripheral vascular resistance, as well as inhibit myocardial contractility and slow down the heart rate, thus exerting the effect of lowering blood pressure. However, hypertension drugs may cause muscle pain and other uncomfortable symptoms after taking them, such as hydrochlorothiazide and metoprolol. Therefore, it is necessary to consult the doctor in time and change the dosage or replace other antihypertensive drugs for treatment after the doctor has comprehensively assessed the condition.