Severe intestinal pycnosis is relatively scary and there is a possibility of cancer. Severe intestinal chemosis is usually a gastric mucosal lesion, when the gastric mucosal tissue damage will lead to epithelial transformation into intestinal mucosal epithelial tissue containing Paneth cells or cup cells, resulting in intestinal epithelial chemosis, which is mainly caused by inflammatory stimulation. Patient symptoms manifest as abdominal pain, diarrhea, and nausea. When intestinal hyperplasia reaches a severe degree because treatment is not carried out as soon as possible, it is currently believed that gastric mucosal intestinal epithelial hyperplasia and gastric cancer have a very close relationship. Therefore, it must be intervened as early as possible to avoid the continuous development of the disease. For drug treatment, you need to take acid-suppressing drugs, and common drugs include omeprazole, pantoprazole and so on. If accompanied by Helicobacter pylori infection, treatment for eradication of Helicobacter pylori is required. Patients also need to have follow-up visits and gastroscopy at least once a year. Usually, they should pay attention to small meals, regular meals, control the temperature of the diet, and eat more protein-rich foods in moderation. Patients with severe intestinal septicemia should pay enough attention, and it is recommended to consult a doctor in time for targeted treatment under the guidance of the doctor, and regular follow-up examination