Elevation of blood ketone bodies is seen clinically in two conditions. In the first case, the patient’s high fasting time is relatively long, or due to other diseases, resulting in several days can not eat, in this case, will lead to elevated blood ketone body, because in the starvation or not eaten state, the body’s energy needs, mainly from the oxidation of fatty acids, blood ketone body is a large number of fatty acid oxidation of metabolic products, in the body will lead to the accumulation of blood ketone elevation. The second condition, diabetic ketoacidosis, is seen in diabetic patients with poor blood glucose control, or in co-infection and other emergency situations leading to ketoacidosis, the pathogenesis is also due to high blood glucose, the body can not effectively use sugar, only fat oxidation and decomposition, resulting in an increase in blood ketone bodies, after excessive elevation, will induce ketoacidosis, resulting in patients with nausea, vomiting This can lead to nausea, vomiting, abdominal pain, diarrhea, decreased blood pressure and even coma. Therefore, if patients have elevated blood ketone bodies, they must pay attention to actively investigate the cause of the disease, and then carry out active treatment.