Elevated blood homocysteine, a biochemical test, is also an independent risk factor for cardiovascular disease. Patients may have elevated blood homocysteine due to malabsorption of folic acid and vitamin B12 in the stomach, as metabolic factors can also cause this condition. When blood homocysteine is elevated, patients are prone to cerebral atherosclerosis, as well as cardiac macrovascular sclerosis, leading to the development of cardiovascular and cerebrovascular disease. Therefore, when a patient has elevated blood homocysteine, it is important to give timely regulation. Normally, patients should eat more green leafy vegetables, and also on medication, patients can also take oral vitamin B12, or methylcobalamin, folic acid, vitamin B6 to reduce the level of homocysteine in the blood and reduce cerebrovascular and cardiovascular risk factors.