High thyroid peroxidase antibodies are indicative of autoimmune thyroiditis, such as Hashimoto’s thyroiditis. Thyroid peroxidase antibody is an autoantibody that attacks and destroys thyroid tissues and cells, causing autoinflammation of the thyroid gland, leading to impaired thyroid function, commonly known as Hashimoto’s thyroiditis, also known as chronic lymphocytic thyroiditis. Thyroid peroxidase antibody is high, if the thyroid function is normal, you can not need to carry out special treatment, regular recheck thyroid function, usually need to low iodine diet, avoid a lot of kelp, nori and so on. In the later stage, most patients will have hypothyroidism with elevated thyroid stimulating hormone and decreased T3 and T4, which requires thyroid hormone replacement therapy. If high thyroid peroxidase antibodies are found, it is recommended to seek medical attention and follow the doctor’s instructions for examination and treatment.