Chronic sinusitis is a common inflammatory disease of the mucous membrane of the sinuses, mostly due to repeated episodes of acute sinusitis, allergen stimulation and other reasons. Patients can take mucolytics, anti-allergy drugs and macrolides to treat the disease, and play a corresponding therapeutic effect. 1. Mucolytic agents: such as eucalyptus pinus enteric soft capsule, standard myrtle oil, oleander drops, etc., can help patients dilute mucus, enhance the activity of the cilia, and faster discharge of nasal secretions. 2. Anti-allergic drugs: commonly used drugs include antihistamines and leukotriene receptor antagonists, which can be used for the treatment of chronic sinusitis with allergic rhinitis, asthma and other diseases. 3. Macrolides: commonly used drugs are clarithromycin or roxithromycin, etc., used in acute attack of chronic sinusitis with bacterial infection or postoperative prevention of infection, which can play a role in down-regulating or inhibiting the occurrence and development of inflammatory lesions. Specific medication, it is recommended that patients under the guidance of a doctor to avoid unauthorized use of medication to cause adverse effects.