Granulomatous vasculitis cannot be cured because granulomatous vasculitis is an autoimmune disease that is more difficult to control and has a poor prognosis because of the damage to the kidneys. Granulomatous vasculitis is a necrotizing vasculitis with granuloma formation and involvement of small and medium-sized vessels. Patients with generally mild symptoms can be relieved with long-term treatment with drugs, but cannot be cured. In patients with renal damage and severe systemic symptoms, the disease can be relieved and controlled in the short term, but recurrent attacks can cause poor results in later treatment. In patients with renal damage, the disease progresses rapidly and can progress to renal failure and uremia, with a high mortality rate. Most patients have skin mucosal damage, which manifests as palpable purpura, polymorphic erythema, necrotizing papules and ulcers on the lower extremities. However, patients are still advised to actively cooperate with their doctors to relieve symptoms, even if they cannot be completely cured. Clinical treatment is based on pharmacological therapy, with common medications such as immunosuppressive agents such as cyclophosphamide and cyclosporine A, glucocorticoids such as prednisone and methylprednisolone, and biological agents such as rituximab, which can provide remission or partial remission in relapsed and refractory cases. Patients with renal disease damage are often treated clinically with plasmapheresis. Patients with granulomatous vasculitis are also advised to take their medications strictly according to medical advice and to enhance nutrition, avoid spicy and irritating foods, prohibit smoking and alcohol, avoid staying up late, and keep their mood happy in daily life.