Granulomatous disease mainly includes the following: 1. Granulomatous disease caused by bacterial infection: the most common is Mycobacterium tuberculosis, but also includes Cryptococcus, Mycobacterium and Pneumocystis, which can cause granulomatous disease. 2. Immune system diseases: such as allergic pneumonia, pulmonary nodulosis, and aspiration pneumonia, filariasis, ascariasis, etc., which may also lead to infectious granulomatous disease. 3, Other etiologies: such as trauma, foreign bodies, and local wrapping may also lead to chronic granulomatous disease. If granulomatous disease is found, it is recommended that patients go to a regular specialized hospital for systematic examination to clarify the diagnosis, and if necessary, puncture biopsy may be required to send pathological tests to clarify the diagnosis, followed by timely symptomatic treatment according to different etiologies.