Early burn wounds are prone to infection, especially in the 3-5 days after the injury, which is the peak period of infection, and improper treatment will deepen the wounds and leave scars. For patients with mild burns and those who are not convenient to go to a specialist hospital for medication change, we will now briefly introduce the recommended early medication change process and precautions for patients or their families to facilitate your correct operation: 1. Frequency of medication change Select the appropriate frequency of medication change according to the temperature, the amount of exudation, the depth of the trauma and whether it is infected. The higher the temperature, the more exudation, the deeper the trauma and the heavier the infection, the more diligent the change of medication. Generally speaking, the dressing should be changed every 1-2 days and not more than 3 days. Note: Once the dressing has penetrated, or the odor has increased, or the pain has worsened. The dressing must be changed daily or even twice a day. 2.Preparation materials In addition to sterile water and medication, some materials are needed to facilitate the dressing change operation. （Optional: disposable bowl, disposable forceps, cotton balls, gauze, adhesive tape, bandages Optional: sterile gloves, dressing 3, the process of changing medication 1) Cleaning the wound: clean the wound with disinfectant (chlorhexidine, Huijan Shutai, Plantron) after wetting with cotton balls, or rinse for dirty wounds. Large wounds can be moistened with gauze and applied wet for a few minutes. The principle is: clean as well as possible without overstimulating the trauma. Take care to extend disinfection appropriately, as the surrounding normal skin can also harbor bacteria without cleaning for several days. 2) Spray the wound with topical growth factors to promote wound healing. (The medication needs to be refrigerated.) 3) Apply silver sulfadiazine cream (white ointment) on gauze to a thickness of about a dollar coin. The function of this ointment is: strong sterilization and prevention of gauze adhesion. Due to the high irritation of sulfadiazine drugs, gel-based drugs are usually used again to reduce their side effects. 4) Squeeze the gel type medication (Plantronics, Ansul, Dextran) on top of silver sulfadiazine, the amount should not be too much, just cover the wound completely. The main effects of gels are: anti-infection, neutralization of sulfadiazine, promotion of necrotic tissue shedding, and promotion of wound healing. Note: The gel alone tends to make the gauze adhere to the wound, so please soak it well when removing it. 5) Dressing: After covering the wound with medicated gauze, the outer layer is then covered with no less than 8 layers (1 piece) of gauze. The dressing needs a certain degree of tightness, otherwise it will affect the absorption of exudate. The gauze is very breathable, so don’t worry that the dressing will cover the wound. Once the gauze penetrates, please change the dressing or blow dry with hair dryer in time. 6) Foam dressing: The new composite foam dressing can be used independently without adding drugs. After spraying the growth factor, it covers the wound. The dressing can have the function of anti-infection and promote healing through its own material characteristics. The use of fully closed dressings can also be used without interfering with bathing. However, it is more expensive. 4. Precautions 1) Sulfadiazine cream feels like pus and has painful manifestations for a few hours after use, but it is not an infection. It can be identified by whether or not the redness and swelling around the wound surface subsides. 2) This process is only applicable to the change of medication for trauma within 2 weeks after the injury. For the change of medication after 2 weeks, please refer to my article “The process of changing medication at home for late trauma”.