Gout patients with fluid accumulation in the metatarsal bones, if the amount of fluid accumulation is small, you can take medication to reduce the formation of fluid, but if the amount of fluid accumulation is large and causes pain and swelling in the area of fluid accumulation, you should go to the hospital to have the fluid extracted and take medication to treat the condition. Gout is a kind of joint inflammation caused by the deposition of urate crystals in the joints, under the stimulation of inflammation in the joints may appear in the bursa of the tissue fluid exudation and effusion, if the effusion is small, you can take diclofenac, colchicine, and other medications, the effusion of a larger amount and cause the corresponding symptoms of the joints, can be carried out by a professional physician to puncture and extraction of joint effusion. For gout patients with joint inflammation and pain, swelling and other symptoms, you can also take indomethacin, celecoxib and other non-steroidal anti-inflammatory drugs to relieve the symptoms, but should be excluded from the contraindications of the corresponding drugs before use. The above drugs should be used under the guidance of a physician, and it is recommended that patients with gout who develop effusion in the metatarsal bones go to the rheumatology and immunology department of a regular hospital for further consultation.