If you have been in contact with the saliva of hepatitis B patient for more than 24 hours, you don’t need to take hepatitis B immunoglobulin in general, but a few special people can consider to take the injection for their own reasons. 1. No need for vaccination: the transmission of hepatitis B virus includes vertical transmission from mother to child, sexual transmission and blood transmission, respiratory tract and digestive tract will not cause transmission of hepatitis B virus, so contact with saliva of hepatitis B patients generally will not cause hepatitis B virus infection. 2. Special need for vaccination: for newborns and other special people, in view of their digestive tract function is not sound, we can consider vaccination of hepatitis B immunoglobulin to block hepatitis B virus infection. If you are overly worried after coming into contact with the saliva of a hepatitis B patient, the best way is to go to the hospital for a hepatitis B penta test to confirm whether you are infected with the hepatitis B virus and whether you have hepatitis B antibodies. The best thing to do is to go to the hospital for a Hepatitis B pentameter test to confirm whether you are infected with the Hepatitis B virus and whether you have the Hepatitis B antibodies.