Many people are very concerned about the test results after a medical examination. However, not many people are able to read and understand the various indicators. Now we will introduce the most common serological indicators of hepatitis B virus (usually called “hepatitis B two-and-a-half”) as follows. The most common serological indicators of hepatitis B virus (often called “hepatitis B half”) are as follows. 1, HBsAg (hepatitis B virus surface antigen), is the shell protein of the hepatitis B virus, which is not infectious in itself. HBsAg only indicates that there has been or is a hepatitis B virus infection, and this alone does not indicate whether the hepatitis B virus is still replicating, so it is not a sign of infectiousness. 2, anti-HBs (hepatitis B surface antibody), is a protective antibody. It is a sign of immunity after infection with hepatitis B. It is also a symbol of hepatitis B cure or tendency to cure. Prevention of hepatitis B through hepatitis B vaccination means to stimulate the body to produce anti-HBs. 3, HBeAg (e antigen), a structural component of the core of the hepatitis B virus, its presence indicates that there is still the presence and replication of the hepatitis B virus in the blood, and is therefore infectious. 4, anti-HBe (e antibody), positive indicates that the hepatitis B virus replication is not active, low or little infectious, is a sign of a longer period of hepatitis B virus infection. If it exists for a long time, it suggests the integration of HBV-DNA and host DNA. However, if HBV-DNA is detected positive at the same time, it means that hepatitis B virus still exists in the blood or the virus has mutated, which is not only infectious, but also may be more harmful to the organism. 5, anti-HBc (core antibody), the main component of which is the IgG type of core antibody. Its positivity is a sign of past or present infection with hepatitis B virus. As with HBsAg, this alone does not indicate whether the hepatitis B virus is replicating.