Inflammatory pseudotumor of the liver should be mainly operated, and the purpose of surgical treatment is to clarify the diagnosis and resect the lesion, but there is no consensus on the surgical method. Generally speaking, inflammatory pseudotumor of the liver in clinical practice is mostly single, and the boundary is clear, and the location of the lesion is superficial and obvious, and it is located in diaphragmatic surface of liver, and the surgical difficulty is not big, so the country advocates surgical resection at present. For inflammatory pseudotumor that cannot be resected, biopsy should be performed to clarify the diagnosis. Inflammatory pseudotumor with jaundice, the lesion is mostly located in the hepatoportal, which is difficult to be resected, and it is feasible to perform choledochal drainage or reconstructive bypass surgery, and if necessary, whole liver transplantation. Inflammatory pseudotumor of the liver develops slowly, the symptoms are mild, and no serious complications and carcinoma are seen, so the prognosis is mostly good.