Nalmefene is an opioid receptor antagonist that can be used mainly to promote wakefulness, detoxification and detoxification of alcohol. Its main effects are first aid for patients with acute drug poisoning, acute alcohol poisoning, and acute opioid toxin poisoning. In addition, it is also effective for patients with hemorrhage, such as acute cranio-cerebral hemorrhage. It is also effective for coma and shock caused by acute cerebral infarction, acute cerebral thrombosis, and acute ischemic cerebrovascular disease attacks. It is also effective in promoting awakening, such as spinal cord injury and coma caused by neurological damage. It also has a strong receptor antagonistic effect on severe alcoholism and relapse after detoxification.