If the fever does not go down after 2 hours of taking ibuprofen, you should check the instructions to see if it is due to insufficient dosage; at the same time, drink plenty of warm water, and at the same time, carry out physical cooling (e.g., warm-water baths, ice caps, cold compresses, fever-reducing patches, etc.); if the bacterial or viral infections are more serious, you can inject antibiotic medicines (e.g., cefaclor, etc.) or antiviral medicines (e.g., oseltamivir, etc.) into a vein under the direction of your doctor, and so on. If the fever does not go down after 2 hours of taking ibuprofen, check the dosage taken according to the instructions to see if it is appropriate, because different dosages are used according to different ages and weights, respectively. You should choose to take the appropriate dose according to the patient’s weight and age; if the fever persists, you can repeat the medication once at an interval of 4 to 6 hours, but not more than 4 times in 24 hours. It is necessary to drink more warm water in time to promote drug metabolism and help sweating, through which the temperature can also be lowered. At the same time, physical cooling, such as warm water bath, ice cap, cold compresses, antipyretic patches and so on. After taking ibuprofen for 2 hours or repeated doses of the drug has not subsided fever, may be the patient’s bacterial or viral infection is heavy, it is recommended to go to the hospital in a timely manner, according to the doctor’s instructions to carry out auxiliary examination, under the guidance of the doctor intravenous antibiotic drugs (such as cefaclor, etc.) or antiviral drugs (such as oseltamivir, etc.), and so on. If the fever does not subside 2 hours after taking ibuprofen or after repeating the medication, you should consult a doctor to find out the cause of the fever and use the medication under the doctor’s guidance so as not to delay the condition.