Apolipoprotein A1 is closely related to atherosclerosis, diabetes, hyperlipidemia and other diseases. Apolipoprotein is a lipoprotein and is a mandatory screening item in cardiovascular diseases. Low Apo A1 is commonly found in the following diseases: 1, cardiovascular disease, the lower the Apo A1, the higher the risk of cardiovascular disease, so low Apo A1 is an independent high-risk factor for atherosclerosis. 2, people with low Apo A1 are prone to diabetes, diabetic patients have elevated blood sugar and metabolic disorders, often accompanied by dyslipidemia, when Apo 3. Also related to familial genetics, such as familial genetic Apo A1 low patients, also prone to atherosclerosis, diabetes, hypertension and other directly related.