The best time to take stomach medicine
Gastric drugs are mainly oral medications used to treat peptic ulcers and acute and chronic gastritis. When taking gastric drugs, we should not only consider the pharmacological effects of the drugs, but also grasp the reasonable time of administration in order to obtain the best results.
1.Gastric motivation drugs
Commonly used drugs: Gastrofacial (methotrexate), domperidone (morpholine), cisapride (Prebios) or mosapride, etc.
Dosing time:It is advisable to take it half an hour before meal. Take the drug before meals, can make the blood concentration of gastrodynamic drugs to reach the ideal level, to facilitate the role of drugs.
2.Antacids
Commonly used drugs: aluminum hydroxide, magnesium oxide, magnesium trisilicate, calcium carbonate, as well as compound preparations such as gastric Shu Ping, cover gastric flat, gastric treatment, gastric Delight (the main component of the antacid), etc..
Dosing time: l~1.5 hours after meal.
The purpose of taking antacids is to neutralize excess stomach acid. The drug is most effective when the stomach contents are near emptying after digestion in the stomach, i.e. 1~1.5 hours after a meal, so that the buffering effect can be maintained for 3~4 hours. If taken immediately after a meal, the effect can only be maintained for about 1 hour.
Note: Gastropin, Gastropin and others are chewable, chewed and taken with better effect.
3.Acid-suppressing drugs
Commonly used drugs: there are many types of acid suppressants, commonly used H2 receptor antagonists and proton pump inhibitors. The former are cimetidine, ranitidine, famotidine, rosatidine, nizatidine, etc., and the latter are omeprazole (Loxac), rabeprazole, lansoprazole, etc.
The latter include omeprazole (Loxac), rabeprazole, lansoprazole, etc. Time of administration: proton pump inhibitors are taken orally before meals or during fasting, while H2 receptor antagonists can be taken before and after meals.
Although the effect of acid inhibitors is not as fast as antacids, but its long duration of action, less side effects, and obvious efficacy, so acid inhibitors are currently the main drugs for the treatment of gastric diseases. The absorption of proton pump inhibitors is easily disturbed by food in the stomach, so they should be taken orally before meals or during fasting. h2 receptor antagonists can be taken before and after meals.
4, anti-H. pylori drugs
Commonly used drugs: proton pump inhibitors (such as omeprazole, etc.), or colloidal bismuth preparations (such as Lizudra, etc.) plus 1 to 2 antibacterial drugs, such as clarithromycin, amoxicillin, metronidazole, etc.
Dosing time: colloidal bismuth preparation should be taken between meals; metronidazole should be taken after meals; clarithromycin should be taken on an empty stomach; amoxicillin should be taken for an unlimited period of time.
Colloidal bismuth preparation can only play the role of killing Helicobacter pylori by direct contact with gastric mucosa, so it should be taken between meals; metronidazole is stimulating to the gastrointestinal tract and should be taken after meals; food will slow down the absorption of clarithromycin, so clarithromycin has the best effect when taken on an empty stomach before meals; and amoxicillin is not affected by food, so there is no restriction on the time of taking.
5.Gastric mucosa protection drugs
Commonly used drugs: colloidal sub raffinate secret, aluminum thioglycollate, magnesium aluminum carbonate, misoprostol, Metzolim-S, etc.
Dosing time: between meals or before bedtime.
The key to affecting the efficacy of gastric mucosa-protective drugs is the concentration of the drug in the stomach and the time the drug is in contact with the gastric mucosa. If there is food in the stomach, it will reduce the concentration of the drug and weaken the efficacy of the drug; on the other hand, food can slow down the rate of gastric emptying of the drug and prolong the contact time between the drug and the gastric mucosa, so the best effect is taken between meals or before bedtime. Note that aluminum thioglycollate tablets should be chewed and served with water.