Babies born to mothers with Hepatitis B need to have a Hepatitis B half-pair test and a liver function test in their first year of life. Hepatitis B, or viral hepatitis B, is a contagious disease caused by infection with the hepatitis B virus, which is mainly transmitted through blood, body fluids and other means of transmission. Babies born to mothers with Hepatitis B need to have blood tests, Hepatitis B half-pair test and liver function tests within one year of age to find out if the baby is infected with viral Hepatitis B in time. Hepatitis B half-pair test requires a blood test, which examines the antigens associated with the hepatitis B virus and the antibodies that the body may produce, including surface antigen and antibody, E antigen and antibody, core antibody, etc. If the baby is positive for hepatitis B surface antibody, it will be detected by a blood test. If the hepatitis B surface antibody is positive and the other items are negative, it means that there are antibodies in the baby’s body to fight against the hepatitis B virus, which can prevent hepatitis B. Therefore, during pregnancy, people with hepatitis B will be able to prevent hepatitis B from occurring. Therefore, patients with hepatitis B need to go to the hospital regularly to check liver function, blood routine, ultrasound and so on during pregnancy. If there are any abnormalities, it is necessary to decide whether it is possible to continue the pregnancy under the joint consultation of obstetricians and infectious diseases doctors, and the baby should be vaccinated against hepatitis B under the guidance of neonatologists after birth.