The location of pressure points in appendicitis can be affected by the thickness of the patient’s abdominal wall fat, the location of the appendix, and the patient’s sensitivity to pain, but fixed pressure pain in the right lower abdomen is the most important sign for the diagnosis of appendicitis. The most common locations of right lower abdominal pressure pain clinically are three: 1) McKay’s point, which is the outer and middle 1/3 of the line between the left and right anterior superior iliac spine and the navel. 2) the right middle 1/3 of the line between the left and right anterior superior iliac spine. 3) the intersection of the line between the right anterior superior iliac spine and the umbilicus and the outer edge of the rectus abdominis muscle. The above three pressure points are the most common signs in patients with appendicitis. The pain of the appendix can be expanded when the inflammation of the appendix worsens, and can even cause pain in the whole abdomen.