Three-year-old children often scratch the anus, may be due to localized skin eczema, pinworms and other causes of perianal itching due to medication can be taken to intervene. 1. Localized skin eczema of the anus: erythema, blisters and other manifestations around the anus can be seen, as well as local itching and pain. It can be intervened through the use of antihistamines such as iproniazine, glucocorticoids such as dexamethasone, and penicillin, cephalosporin and other medications if combined with symptoms of localized suppurative infections. 2. pinworm disease: insect body stimulation of the perianal skin may lead to local itching, can be diagnosed by fecal examination, clinical commonly used albendazole and other anthelmintic drugs for intervention. Children with symptoms of scratching the anus are recommended to go to the hospital in a timely manner, a clear diagnosis, and follow the doctor’s instructions for reasonable treatment; the above drugs need to be used under the guidance of the clinician.