Severe radiation enteritis can be accompanied by varying degrees of anemia. On the one hand, nausea and abdominal pain caused by radiation enteritis can affect the patient’s eating, and long-term poor food intake can lead to malnutrition anemia; on the other hand, long-term intestinal bleeding or hemorrhage in patients with radiation enteritis can be accompanied by hemorrhagic anemia. In addition to improving the patient’s nutritional status (non-irritating, easy to digest, nutritious, small and frequent meals), active hemostatic measures (e.g. hemostatic drugs, endoscopic hemostasis, surgical hemostasis, etc.) are also essential for the treatment of anemia complicated by radiation enteritis. Take care to avoid taking unauthorized medications, especially those that may aggravate bleeding, such as aspirin. Blood transfusion therapy should be considered for those with severe anemia complicated by radiation enteritis, especially when the hemoglobin is below 70 g/l. Of course, there are some potential complications of blood transfusion therapy, the common ones are allergic reaction, febrile reaction, and in severe cases, hemolytic reaction and transmission of certain viral diseases. However, with strict observation, the risk can be greatly reduced.