Diagnosis of ureaplasmosis needs to be combined with a number of indicators to make a comprehensive judgment, mainly including: urine volume, urine routine, antidiuretic hormone (ADH) levels, water-restriction – pressor test, pituitary MRI and so on. 1. Urine volume: the urine volume of patients with ureaplasmosis increases compared with the original, and the general urine volume will be more than 4000ml/24h. 2. Urine routine: urine specific gravity is less than or equal to 1.010, urine osmolality is lower than plasma osmolality, usually less than 300mosm/kgH2O. 3. Antidiuretic hormone (ADH): patients with central uremia will have a decrease or lack of, patients with renal uremia ADH level is not low, or even higher. 4. Water-restriction-pressin test: (1) Normal: after water fasting, blood volume decreases, hypothalamic ADH secretion increases, urine volume decreases, urine specific gravity and urine osmolality increase, blood osmolality does not change. (2) Central uremia: decreased blood volume after water fasting, insufficient or lack of ADH secretion, no significant decrease in urine volume, no increase in urine osmolality, increase in blood osmolality, and response to pressor. (3) Nephrogenic uremic syndrome: blood volume decreases after water restriction, body’s response to ADH is insufficient, urine volume does not decrease significantly, urine specific gravity and urine osmolality do not increase, blood osmolality may increase, and there is no response to pressor. 5. Pituitary MRI: For patients with central uremia, there may be a loss of high signal in the neuropituitary gland, thickening of the pituitary stalk, interruption of the pituitary stalk and other manifestations. Patients who are suspected of having uremic syndrome are recommended to consult a doctor in time, complete the relevant examinations under the guidance of the doctor, make a clear diagnosis and timely treatment.