Gallbladder polyps can be caused by hyperplasia or crystalline deposits. Gallbladder stones can be associated with various factors, mainly cholesterol stones or mixed stones and melanin stones. 1. Gallbladder polyps refer to the lesions that bulge or protrude into the gallbladder cavity, and are classified as with or without tips, and can be divided into tumor polyps and non-tumor polyps. Cholesterol polyps are cholesterol crystals deposited on the mucosal surface of the gallbladder, inflammatory polyps are hyperplasia of the mucosa of the gallbladder, and adenomatous hyperplasia is a benign hyperplastic lesion of the wall of the gallbladder, which can cause cancer in a few cases, and a few of them have pain in the right upper abdominal area, loss of appetite, nausea and vomiting. 2. Gallbladder stones may be related to dietary habits, cholestasis, high-fat diet and other factors, mainly cholesterol stones, cholesterol-based mixed stones and melanin stones, most patients are asymptomatic, and a few may cause biliary colic when eating greasy food, having a full meal, or sleeping in a different position. It is worth noting that gallbladder polyps and gallbladder stones can coexist and be mutually causative. If gallbladder polyps are combined with gallbladder stones, laparoscopic cholecystectomy is usually recommended. After the diagnosis of gallbladder polyps and gallstones is confirmed, it is recommended to seek prompt medical attention and imaging (e.g., ultrasonography) to determine the treatment plan and follow the doctor’s instructions.