Which is more effective, levetiracetam or sodium valproate, should be based on their indications; both drugs can be used to treat epilepsy, but each treats different types of epilepsy. Levetiracetam is mainly used for the addition of partial seizures in adults and children; sodium valproate can be used to treat generalized epilepsy and partial epilepsy. 1. Levetiracetam: mainly used in adults and children over 4 years of age for the additional treatment of partial seizures. Common adverse reactions include drowsiness, ataxia, amnesia, dizziness, headache, convulsions, hyperkinesia and tremor. If the patient is allergic to levetiracetam or allergic to pyrrolidone derivatives should be prohibited. 2. Sodium valproate: It can be used for the treatment of generalized epilepsy, including myoclonic seizures, apoplectic seizures, atonic seizures, tonic clonic seizures and mixed seizures, etc.; it can also be used for the treatment of partial epilepsy, including complex partial seizures, partial secondary generalized seizures, simple partial seizures, and it can be used for the treatment of bipolar disorder as well. Adverse effects of taking sodium valproate mainly include nausea, stomach pain and diarrhea, etc. It should be contraindicated if the patient is allergic to valproate, valproate amide, bivalproate, or any of the ingredients in this product. Patients should be contraindicated if they have liver disease or significant hepatic impairment. When taking the above drugs, patients should take them correctly according to the doctor’s instructions, and should not take them privately.