Oral warfarin is slow to take effect and usually achieves full anticoagulation in about three days. Within three days the body is left in a hypercoagulable state due to the inhibition of the natural antithrombotic protein cells, which aggravates or prevents blood clots from occurring. To prevent this, warfarin use needs to be regulated with other anticoagulants, such as low molecular heparin, which is used to inhibit the hypercoagulable state during the regulation process, and can be discontinued after three days when warfarin is fully effective.