Patients with fever inside the bones commonly have the following causes: First, septic infection: such as septic osteomyelitis, patients will have clinical symptoms of fever inside the bones, along with systemic clinical manifestations, such as generalized fever, restricted joint movement, and even inability to walk with weight, and patients will experience severe wasting and malnutrition. Secondly, acute attack of gout: gout can involve bones and joints, muscles, ligaments and other tissues, which will also lead to clinical symptoms of fever inside the bones, and accompanied by severe pain, swelling, limited activities, and the examination of serum uric acid will find a significantly higher value. The clinical symptoms of fever inside the bones must be taken very seriously. If there is infection, timely anti-infection treatment should be carried out to avoid causing osteonecrosis and even affecting the function of the limb.