What are the manifestations of diabetes mellitus?

  What is diabetes?  Diabetes is a series of metabolic disorders of sugar, protein, fat, water and electrolytes caused by genetic factors, immune dysfunction, microbial infections and their toxins, free radical toxins, mental factors and other pathogenic factors that cause hypoglycemia and insulin resistance in the body. In typical cases, there are symptoms such as polyuria, polydipsia, polyphagia and lethargy.  What are the symptoms of diabetes mellitus?  The symptoms of diabetes can be summarized as “three more and one less”, the so-called “three more” refers to “more food, more drink, more urine”, “one less The so-called “three more” refers to “more food, more drink, more urine”, “one less” refers to “weight loss”.  (1) more food: due to a large number of urine sugar loss, such as daily loss of sugar more than 500 grams, the body is in a semi-starvation diabetes environmental factors, the lack of energy needs to replenish the appetite caused by hyper-appetite, increased food consumption. At the same time, because of high blood sugar stimulates insulin secretion, so patients are prone to hunger, hyperphagia, always have the feeling of not being full, and even eat five or six times a day, the main food up to 1 ~ 1.5 kg, side dishes are also significantly more than normal people, but still can not meet the appetite.  (2) Drinking more: Due to excessive urination, too much water is lost and intracellular dehydration occurs, which stimulates the thirst center, resulting in thirsty drinking and an increase in the amount and number of drinks as a way to replenish water. The more you urinate, the more you drink, forming a positive relationship.  (3) Polyuria: The volume of urine increases, reaching 3,000 to 5,000 ml per day and night, up to 10,000 ml or more. The number of urination also increases, one or two hours may urinate 1 time, some patients even up to more than 30 times per day and night. Diabetic patients with increased blood sugar concentration, the body can not be fully utilized, especially the glomerular filtration and can not be completely reabsorbed by the renal tubules, resulting in the formation of osmotic diuresis, polyuria. The higher the blood sugar, the more urine sugar excreted, the more urine volume.  (4) Wasting (weight loss): Due to insufficient insulin, the body cannot make full use of glucose, so that fat and protein decomposition is accelerated to replenish energy and calories. As a result, carbohydrates, fats and proteins in the body are consumed in large quantities, coupled with the loss of water, the patient loses weight and body weight, and in severe cases, the weight can be reduced by tens of pounds, resulting in fatigue and weakness, and mental inactivity. Similarly, the longer the duration of the disease, the higher the blood sugar; the more serious the disease, the more obvious the wasting.