Whether 0.5cm gastric mesenchymal tumor needs surgery needs to be judged with the actual situation, and cannot be generalized, it is recommended to be treated under the guidance of professional doctors. Gastric mesothelioma is a kind of gastrointestinal mesenchymal tumor, which occurs in the stomach and originates from mesenchymal tissues, it is a non-epithelial and less malignant tumor, usually manifested as abdominal distension, vomiting blood, black stools and other symptoms, and part of the population does not have any special reaction. Whether a small mesenchymal tumor of 0.5 cm needs surgery or not is not only based on the symptoms, but also needs to be combined with and refer to the tumor location, ultrasound endoscopy results, and changes in tumor follow-up to decide whether surgery is needed or not. Therefore, the treatment of gastrointestinal mesenchymal tumors is based on the principle of individualized comprehensive treatment, according to the specific conditions of the patient’s tumor, comprehensive treatment, the most substantial eradication of the tumor, to improve the cure rate, daily life should be a light diet, regular work and rest, and appropriate participation in sports, to enhance physical fitness.