Adult ventricular septal defect includes general treatment, medication and surgery, and the specific treatment should be formulated according to the condition. 1. General treatment: patients with ventricular septal defect should pay attention to rest, avoid excessive exertion, avoid excessive intake so as not to increase the cardiac load, low-salt diet, and prevent respiratory tract infection. 2. Drug therapy: some patients may have different degrees of cardiac insufficiency, need to give drugs to reduce the cardiac load, such as furosemide, isosorbide nitrate, etc., combined with atrial fibrillation should be given to control the heart rate of the drug therapy, such as digoxin, metoprolol and so on. 3. Surgical treatment: patients with surgical indications should have early surgical treatment to effectively improve the abnormal reflux of blood, while some patients do not have surgical opportunities and can only be treated with medication. Patients with ventricular septal defects should be evaluated under the guidance of physicians to formulate specific treatment plans.