Large dandruff crusts on the scalp, consider and often scratching, seborrheic dermatitis, psoriasis and other factors related to the topical medication, topical medication, physical methods of treatment. 1. Frequent scratching: If patients usually do not pay attention to hygiene, the phenomenon of large dandruff scabs on the scalp is likely to occur in the local area. Patients should avoid scratching the affected area, do a good job of scalp cleaning, you can use iodine pomade to disinfect the local, and so on the scabs naturally fall off, the affected area will be restored. 2. Seborrheic dermatitis: If the patient’s scalp is infected by Malassezia, it will stimulate the local skin itching, scratching will lead to breakage of the affected area, the formation of dandruff and scabs. Patients can follow the doctor’s instructions to use ketoconazole, itraconazole and other drugs can play an anti-inflammatory, anti-itching, anti-dandruff effect, to keep the scalp clean. 3. Psoriasis: Psoriasis can also cause the patient’s lesions covered with white scales and scabs. Patients can go to the hospital for photochemotherapy, which can be used topically with vitamin D3 derivatives such as carbotriol or tacalcitol. The use of immunosuppressants such as methotrexate and cyclosporine A as prescribed by the doctor can provide relief. Large dandruff crust on the scalp, it is recommended to go to the hospital in a timely manner, and by a professional physician to diagnose and treat, do not blindly use drugs.