Abnormal prothrombinogen high 200+ is defined as abnormal prothrombinogen 200μg/L or more. Abnormal prothrombinogen 200μg/L or more, may be vitamin K deficiency, chronic liver disease, primary liver cancer, etc..
1. Vitamin K deficiency: the coenzyme agent of prothrombin is vitamin K. When the organism is deficient in vitamin K, it can not synthesize prothrombin normally, and can only synthesize abnormal prothrombin, which will lead to elevated prothrombin.
2. Chronic liver disease: due to the decreased function of liver to synthesize prothrombin, it can only synthesize abnormal prothrombin, which means that the abnormal prothrombin is more than 200μg/L.
3. Primary hepatocellular carcinoma: due to the abnormal synthesis of thrombin by cancer cells and insufficient carboxylation of prothrombin precursors, a large amount of abnormal prothrombin will be generated, which can be manifested as abnormal prothrombin with a high level of 200 μg/L or more.
Abnormal prothrombinogen high 200μg/L or more, there may be other causes, patients are recommended to consult the doctor in time, need to receive diagnosis and treatment under the guidance of the physician.