According to archaeological discoveries, cranial repair surgery has been in use as early as 7,000 to 8,000 years ago, only that it was simpler and rougher back then. It can be said that cranial repair has accompanied human civilization all the way to the present. Over the past thousands of years, cranial repair surgery has not only experienced continuous improvement in technology, but also continuous innovation in repair materials. Some patients ask what is the best material for cranial bone repair surgery, we can first look at what materials have been used, and then finally give the answer: Cranial bone repair material classification: 1, animal bone. In history, people have used animal cranial bone transplantation to the human body to carry out cranial bone repair, there is a certain degree of progress, but it is difficult to avoid all kinds of problems, and gradually abandoned. 2.Autogenous bone. Later, autogenous bone was gradually used for cranial bone repair, and successively there were tibia, rib, shoulder bone, skeleton and sternum for cranial bone repair, but most of them were eliminated because of the limited material, the need to open up the second surgical area, the grafts could be absorbed, and the difficulty of shaping. Non-metallic materials. Historically, non-metallic bone substitutes have been used for cranial bone repair, including celulose, methacrylic resin, polyethylene, silicone rubber, coral, ceramics, light apatite, and calcium phosphate bone cement, etc., but they are no longer in use due to various problems. 4. Metallic materials. Once used metals are gold, silver, aluminum, lead, platinum, tantalum, live alloys, stainless steel and titanium, etc., but in addition to titanium because most of which can be corroded, can be thermally conductive, relatively impervious to X-rays and foreign body reaction and was eliminated. Titanium mesh material is still widely used in clinical practice, but more or less there are some problems, there is a certain chance of infection and rejection, molding, thermal insulation, radiation and other issues. 5, PEEK material. This is currently a very ideal cranial bone repair materials, is a special polymer materials, its properties and autologous skull is very close to the clinical effect is good, and gradually become the new trend of cranial bone repair materials.