Urine microalbumin and creatinine ratio of 400 indicates that there is a moderate amount of protein in the urine, you need to improve the quantitative urine protein, renal function and other related tests, if necessary, renal puncture biopsy, clear cause of the cause of treatment.
Normal human urine microalbumin creatinine ratio is less than 30mg/g, 30~300mg/g belongs to micro-proteinuria, more than 300mg/g belongs to clinical proteinuria, most of them are caused by diseases, more common in diabetic nephropathy and various primary glomerulonephritis.
At the same time can not rule out the possibility of physiological conditions, such as fever, strenuous exercise, nutcracker syndrome.
At this time, it is necessary to improve the 24-hour urine protein quantification, renal function, autoantibodies, anti-phospholipase A2 receptor antibodies, vasculitis antibodies and other tests to determine the cause of the disease. If it is relatively difficult to determine the cause of the disease, renal puncture biopsy is necessary to help identify the cause of the disease.
Symptomatic treatment will be carried out according to different causes, for example, diabetic nephropathy requires strict control of blood glucose and blood pressure. Primary glomerulonephritis may be treated with glucocorticoids (e.g., prednisone acetate) and other immunologic agents (e.g., cyclosporine, tacrolimus).
Urine microalbumin and creatinine ratio of 400 has many other reasons, it is recommended that the patient regular hospital consultation, under the guidance of the physician to improve the relevant examination, a clear diagnosis, according to the different causes of the disease, follow the doctor’s advice to the appropriate treatment.