There is mucus in stool for a long time for about five or six years, which is mostly considered to be gastroenteritis, inflammatory bowel disease, intestinal tumors and other diseases, and can be adjusted by general treatment, medication such as norfloxacin, mesalazine, lactobacillus and other medications, and surgical treatment. 1. General treatment: patients should pay attention to adjusting their diet, avoiding irritating and difficult-to-digest foods such as chili peppers, ginger, deep-fried oil, etc., and keeping the diet light and nutritionally balanced. At the same time, quit smoking and drinking, ensure enough rest, avoid staying up late, overwork, and strengthen exercise to enhance their physical fitness. 2. Medication: The medication for long-term mucus in the stool caused by different diseases is different. If it is due to unclean diet and other causes of gastroenteritis, can take norfloxacin, cefixime and other antibiotics for anti-infective treatment; if it is due to ulcerative colitis, can take LiuZiShiShengPiDi, mesalazine and other drugs. If it is due to intestinal flora disorders, you can take lactobacillus, bifidobacteria and other intestinal probiotics; if it is due to peptic ulcer, chronic gastritis and other diseases, you can take omeprazole, colloidal bismuth and other drugs. 3. Surgical treatment: If it is caused by colon cancer, rectal cancer, intestinal polyps and other diseases, surgical treatment can be considered. When the patient has mucus in the stool for a long time for about five or six years, it is recommended to consult a doctor in time and accept the treatment actively, and the medicine should be taken in strict accordance with the doctor’s prescription, and should not be used by oneself, so as to avoid delaying or even aggravating the condition.