If uncontrollable frowning occurs during sleep, it is due to the following reasons.1. The most common reason is the abnormal discharge of brain cells, usually in the substantia nigra striata of the cerebral cortex, the impulse of neurons with abnormal activity occurs, which is mostly due to the seizure of epilepsy in the past, and the abnormal impulse of nuclei of the brain cells and the discharge occurs.2. There is a transient transient cerebral ischemic seizure in the sleep for patients with a history of stroke or patients with acute cerebrovascular disease are prone to transient cerebrovascular ischemic seizures during sleep. Patients with a history of stroke or acute cerebrovascular disease are prone to transient cerebrovascular ischemic seizures during sleep, especially in patients with atherosclerotic plaque formation in the cerebral arteries, which may result in uncontrollable frowning or nervousness during sleep.