Biliary tract drain infections should be replaced in a timely manner, and appropriate use of iodophor or hydrogen peroxide to disinfect, if the cause of systemic symptoms can also use drugs such as cephalosporin. Biliary drain infection is mostly caused by improper care, the drain should be replaced in time, and the local wound should be sterilized with iodophor or hydrogen peroxide, and if there is purulent exudate, it should also be cleared in time. If it causes systemic symptoms, such as chills, fever, fatigue, etc., you can also use antibiotics, such as ceftriaxone sodium, levofloxacin and other drugs for treatment. Daily to strengthen the care of the drainage tube, disinfection should be carried out every day to prevent inflammation and infection, to ensure that the drainage tube is smooth, conducive to the discharge of drainage fluid, the use of medication please follow the doctor’s instructions.