Hepatitis B is caused by infection with the hepatitis B virus and is a chronic infectious disease that cannot be completely cured because it cannot eradicate the hepatitis B virus DNA from the patient’s body, but can only control the patient’s condition from deteriorating. The hepatitis B virus may cause a chronic infection after it infects the body. In chronic infections, the body’s immune system does not react strongly to the infection to clear it, and when the hepatitis B virus escapes from the immune system, it can enter the liver cells and cause a chronic and persistent infection. The treatment of hepatitis B mainly applies antiviral drugs nucleoside analogues, although it can inhibit the replication of the virus for a long time, but still some of the virus will exist in the liver cells and cannot be completely eliminated, so the virus will continue to multiply after the antiviral drugs are discontinued, so it is more difficult to cure hepatitis B. Patients with chronic hepatitis B should pay attention to rest and avoid exertion. They should quit smoking and drinking, and their diet should be high in protein and vitamins and easily digestible food, but there is no need to overemphasize high nutrition, which may cause fatty liver. Patients should establish confidence, active treatment and regular review.