The differences between nifedipine controlled-release tablets and extended-release tablets are different half-life, different usage and different release rate. 1. Different half-life: the half-life of nifedipine controlled-release tablets is longer, usually 24 hours, while the half-life of nifedipine extended-release tablets is shorter, usually 12 hours. 2. Different usage: Nifedipine controlled-release tablets are usually taken once a day, while nifedipine extended-release tablets may need to be taken once or twice a day, depending on the patient’s condition. 3. Different release speeds: Although the main ingredient of both drugs is nifedipine, the release of nifedipine controlled-release tablets is relatively slow, but it is a uniform release, while nifedipine extended-release tablets release at a fast and uneven rate. Nifedipine controlled-release tablets and extended-release tablets must be guided by a doctor, not to use the drug at will on their own, and when using the drug, pay attention to those who are allergic to nifedipine are prohibited.