Neonatal erythema can subside by itself in 7~10 days if the symptoms are mild, while severe neonatal erythema can be treated with medication. Neonatal erythema may be caused by external stimulation after birth, resulting in non-specific reaction or reaction with some antigens in the mother’s body, and the mild cases are not connected into lumps, with small area, and can subside by themselves in 7~10 days. No special treatment is needed. However, in more serious cases, glycerite lotion or zinc oxide ointment can be chosen. At the same time, avoid contact with allergic substances as well as sunlight and other factors of stimulation can generally subside in about 14 days. Erythema neonatorum should be differentiated from eczema, which is mostly granular changes accompanied by marked itching, while erythema is less itchy and the child is less likely to cry. Mild to moderate neonatal erythema, no special treatment, as long as the skin cleanliness can be ensured. If severe cases can be selected under the guidance of the doctor with glycerine lotion or zinc oxide ointment, because it is not an infectious disease, so there is no need to isolate the treatment, to avoid exposure to sunlight and too much blowing into the cold air.