Naloxone this drug, mainly as an opioid receptor antagonist to use, it itself is no pharmacological activity, but can antagonize all kinds of opioid receptors, that is, it can be used for anesthesia postoperative antagonism of opioid drugs. So it can relieve opioid-induced respiratory depression and promote patient awakening, and it can also be used for opioid overdose, and then it can be used to antidote, like ethanol intoxication in patients, or to antidote with this drug. This drug can be administered intravenously or intramuscularly, and can be taken sublingually for the treatment of acute ethanol intoxication, but cardiovascular disease or hepatic disease, renal insufficiency, such patients should be used with caution, and overdose may result in severe hypertension or hypotension, cognitive impairment, and behavioral abnormalities, so it requires enhanced monitoring to make sure to avoid drug overdose.