Is Minoxidil applicator still effective if I stop using it and use it again? The answer to this question is that if Minoxidil Apply was effective before, it will still be effective if you use it again now. Minoxidil is a topical medication that is mainly used for male pattern baldness and alopecia areata. When using this medication, you should be careful to wash your hair and dry it completely before applying the application evenly, starting from the center of the affected area and massaging it with your hands for 3-5 minutes. Regardless of the size of the affected area, the dosage should not exceed 2 ml per day, because the use of too large a dose of minoxidil, after its absorption, may cause some adverse reactions, for example, it may cause tachycardia, it can induce angina pectoris, and some problems with postural hypotension may occur. If the previous use of minoxidil rub was effective in promoting hair growth, reuse after discontinuing use for a period of time is still theoretically effective.