Metformin extended-release tablets taken at night with meals can better play a blood sugar lowering effect. Metformin extended-release tablets belong to the biguanide class of hypoglycemic drugs, can reduce hepatic glucose production and intestinal absorption of glucose, and then improve insulin sensitivity, reduce basal and postprandial glucose, can be used to treat patients with type 2 diabetes mellitus who have difficulty controlling blood glucose with diet and physical exercise alone. Patients who are allergic to this drug, severe renal failure, heart failure and other tissue hypoxia diseases, acute metabolic acidosis. Metformin extended-release tablets are recommended to be taken at night with meals, because blood sugar will begin to rise after eating, and taking Metformin extended-release tablets at this time can well reduce postprandial blood sugar, and at the same time, due to the extended-release effect of Metformin extended-release tablets, it can also control the fasting blood sugar of the next day. Adverse reactions such as palpitations, hot flashes, hypoglycemia, headache, dizziness, liver function abnormalities, hepatitis, nausea, vomiting, and diarrhea may occur after use. Patients who need to use Metformin Extended-Release Tablets should use the medication under the supervision of a doctor.