Pain in the lower right side of the chest should be examined with a plain CT scan of the chest. This is because it is most commonly an infection of the lung tissue and is combined with pleurisy on the affected side. It may also be accompanied by fever, and intravenous anti-infection treatment should be chosen in time, and deep breathing functional exercises should be performed to be able to promote the recovery of the disease. If complicated by the formation of pleural effusion, there will also be chest tightness and restricted breathing, and if necessary, thoracentesis under local anesthesia should be chosen to drain the fluid, which can also alleviate the discomfort. Some patients with liver diseases, especially liver malignant tumors, which involve the diaphragm and manifest as pain in the lower right side of the chest, can be treated by interventional embolization or systemic intravenous chemotherapy to control tumor development.