Eperistat, or Epalrestat, can be used along with pancreatic kininogenase for the treatment of complications caused by diabetes mellitus.
Epalrestat is mainly used to prevent, improve and treat neuropathy, such as numbness of hands and feet, blurred vision and other complications that occur in diabetic patients. Adverse reactions such as liver function abnormalities, abdominal pain, nausea, and a feeling of tiredness may occur; use with caution in people with a history of allergies.
Pancreatic kininogenase mainly plays a role in improving the retinal blood supply disorders and peripheral vasculopathy caused by diabetic complications, and at the same time, it can reduce the amount of urinary serum protein excretion in patients with early diabetic nephropathy. It is contraindicated in patients with hypersensitivity to the drug, tumors, increased intracranial pressure, heart failure, acute myocardial infarction and acute bleeding. Occasionally, there are adverse reactions such as rash, skin itching and stomach discomfort and tiredness.
The simultaneous use of both can effectively treat peripheral neuropathy in diabetic patients, and play a role in the prevention and treatment of diabetic complications. The above medications are used under the guidance of a doctor, avoid self-medication.