Numbness of the face and mouth is mainly seen in the following diseases: first, cerebral infarction, mostly in elderly patients, with previous hypertension, diabetes, hyperlipidemia and other underlying diseases, acute or subacute onset, in addition to numbness of the mouth and face can also be accompanied by limb weakness, sensory impairment, choking and coughing, swallowing difficulties, slurred speech, cranial CT or cranial magnetic resonance examination can be further clarified. Second, cerebral hemorrhage, cerebral hemorrhage is seen in middle-aged and elderly patients, induced after exertion or emotional excitement, the patient’s disease is more acute, the symptoms are similar to cerebral infarction, some patients can also be accompanied by obvious headache, and the hemorrhagic foci can be seen on cranial CT. Third, Green-Barre syndrome, the patient’s face is symmetrical, accompanied by numbness of the hands and feet, and some patients may also be accompanied by weakness of the limbs, breathing difficulties and other symptoms. Therefore, it is recommended to visit the neurology department for symptoms of numbness in the face and mouth.