Drinking the next day diarrhea may be alcohol damage to the gastrointestinal mucosa, may be acute gastroenteritis, may also be chronic colitis. 1. Alcohol damage to the mucous membrane of the gastrointestinal tract: wine contains more alcohol, the main component is ethanol, but also metabolized to produce acetic acid, ethanol, acetic acid can stimulate and damage the mucous membrane of the gastrointestinal tract, resulting in gastrointestinal tract disorders, dyspepsia, diarrhea can be a symptom. 2. Acute gastroenteritis: drinking and eating unclean food, leading to pathogens into the digestive tract, stimulating the gastrointestinal mucosa, resulting in mucosal congestion, edema, oozing and even bleeding, leading to diarrhea the day after drinking. 3.Chronic colitis:autoimmune and other causes of inflammation of the colon, such as ulcerative colitis, Crohn’s disease, repeated chronic inflammation of the intestinal tract, in the alcohol stimulation, intestinal inflammatory response heavy, resulting in diarrhea symptoms. Drinking the next day diarrhea should be to the hospital, under the guidance of the doctor treatment.