Tongue cancer is a common oral malignant tumor, mostly squamous cell carcinoma with infiltrative growth, which is prone to metastasis in the lymph nodes of the neck in early stage. For determining whether tongue cancer is present, clinical examination can be used to make a clear diagnosis. 1.Self-examination: If there is an ulcer on the tongue that has not healed for more than 2 weeks, it is recommended to visit a dental specialist hospital to exclude the diagnosis of tongue cancer; 2.CT examination: CT plain scan ranges from the skull base to the level of clavicle, if there is tongue cancer, it can show that the CT value of the mass is about 25-38 HU, the density is not uniform, and the enhanced scan shows mild or moderate enhancement with necrotic cystic area, and the lesion is circularly enhanced; 3. MRI examination: MRI scan shows lesion more clearly than CT, T1WI shows heterogeneous equal and low mixed signal; T2WI shows heterogeneous high signal, enhancement shows heterogeneous and obvious intensification of lesion and no enhancement of necrotic cystic area; 4.Pathological examination: most of the pathological specimens of tongue cancer patients are grayish red or grayish white, irregular in shape, under light microscope, cancer cells are nested in sheets or masses, infiltrating The nuclei of cancer cells are large, ovoid or shortened, with red stained cytoplasm and obvious heterogeneity, and obvious formation of cancer beads, accompanied by interstitial fibrous tissue hyperplasia and inflammatory cell infiltration.